TTF1 antibody
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935106861
info@markelab.com
name
TTF1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09090
tested applications
ELISA, WB, IHC
Description
Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NK2 homeobox 1 (TTF1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 4D3 |
| Observed MW | 42 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P43699 |
| Gene ID | 7270 |
| Alias | Transcription termination factor 1 (TTF-1),RNA polymerase I termination factor,Transcription termination factor I (TTF-I),TTF1 |
| Background | Antibody anti-TTF1 |
| Status | RUO |
| Note | Mol. Weight 42 kDa |
Descripción
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TTF1-Specific antibody
TTF1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. It plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5, TTF1 recovers DNA-binding activity. The antibody is specific to TTF1.
Ver Producto