TTF1-Specific antibody
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935106861
info@markelab.com
name
TTF1-Specific antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08928
tested applications
ELISA, WB
Description
TTF1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. It plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5, TTF1 recovers DNA-binding activity. The antibody is specific to TTF1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | transcription termination factor, RNA polymerase I (TTF1) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:1000-1:10000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 7C4 |
| Observed MW | 43 kDa, 66 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15361 |
| Gene ID | 7270 |
| Alias | Transcription termination factor 1 (TTF-1),RNA polymerase I termination factor,Transcription termination factor I (TTF-I),TTF1 |
| Background | Antibody anti-TTF1 |
| Status | RUO |
| Note | Mol. Weight 43 kDa, 66 kDa |
Descripción
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TTF1-Specific antibody
TTF1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. It plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5, TTF1 recovers DNA-binding activity. The antibody is specific to TTF1.
Ver Producto