GFUS antibody
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Description
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | tissue specific transplantation antigen P35B (GFUS) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 40 kDa, 68 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13630 |
| Gene ID | 7264 |
| Alias | GDP-L-fucose synthase,GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase,Protein FX,Red cell NADP(H)-binding protein,Short-chain dehydrogenase/reductase family 4E member 1,GFUS,SDR4E1,TSTA3 |
| Background | Antibody anti-GFUS |
| Status | RUO |
| Note | Mol. Weight 40 kDa, 68 kDa |
Descripción
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GFUS antibody
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
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GDP-L-Fucose Synthetase (GFUS) Antibody is a Rabbit Polyclonal antibody against GDP-L-Fucose Synthetase (GFUS). Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
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