TSG101 antibody
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | tumor susceptibility gene 101 (TSG101) |
| Host | mouse |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000 - 1:10000; IHC: 1:200 - 1:1000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 1C6 |
| Observed MW | 44 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | protein A+G purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC,FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q99816 |
| Gene ID | 7251 |
| Alias | Tumor susceptibility gene 101 protein,ESCRT-I complex subunit TSG101,TSG101 |
| Background | Antibody anti-TSG101 |
| Status | RUO |
| Note | Mol. Weight 44 kDa |
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TSG101 antibody
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
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