TRPV6 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine(PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin(By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification(PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | transient receptor potential cation channel, subfamily V, member 6 (TRPV6) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:200-1:1000; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 82 kDa,70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IF, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H1D0 |
| Gene ID | 55503 |
| Alias | Transient receptor potential cation channel subfamily V member 6 (TrpV6),CaT-like (CaT-L),Calcium transport protein 1 (CaT1),Epithelial calcium channel 2 (ECaC2),TRPV6,ECAC2 |
| Background | Antibody anti-TRPV6 |
| Status | RUO |
| Note | Mol. Weight 82 kDa, 70 kDa |
Descripción
Related Products
TRPV6 antibody
Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine(PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin(By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification(PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Ver Producto
Transient Receptor Potential Cation Channel Subfamily V Member 6 (TRPV6) Antibody
Rabbit Polyclonal against the TRPV6 protein.
Ver Producto
Transient Receptor Potential Cation Channel Subfamily V, Member 6 (TRPV6) Antibody
TRPV6 Antibody is a Rabbit Polyclonal against TRPV6.
Ver Producto