anti- TRPC4AP antibody

Descripción

Substrate-specific adapter of a DCX(DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.

Características del producto

clonality

monoclonal

reactivity

human

immunogen target

transient receptor potential cation channel, subfamily C, member 4 associated protein

host

Mouse

isotype

IgG1

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC

observerd MW

91 kDa

purity

≥95% as determined by SDS-PAGE

purification

Protein A+G purification

recommended dilution

WB: 1:500-1:5000; IHC: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

TRPC4AP

alias

C20orf188, Protein TAP1, Protein TRUSS, Trp4 associated protein, Trpc4 associated protein, TRPC4AP, TRRP4AP, TRUSS

uniprot id

https://www.uniprot.org/uniprotkb/Q8TEL6

gene id

https://www.ncbi.nlm.nih.gov/gene/26133

note

This product is for research use only.

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