TRIP13 antibody
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Description
Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks(DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | thyroid hormone receptor interactor 13 (TRIP13) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 49 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15645 |
| Gene ID | 9319 |
| Alias | Pachytene checkpoint protein 2 homolog,Human papillomavirus type 16 E1 protein-binding protein (16E1-BP, HPV16 E1 protein-binding protein),Thyroid hormone receptor interactor 13,Thyroid receptor-interacting protein 13 (TR-interacting protein 13, TRIP-13),TRIP13,PCH2 |
| Background | Antibody anti-TRIP13 |
| Status | RUO |
| Note | Mol. Weight 49 kDa |
Descripción
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