TRIM6 antibody
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935106861
info@markelab.com
name
TRIM6 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08991
tested applications
ELISA, IHC, WB
Description
E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells(By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response(PubMed:24882218).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | tripartite motif-containing 6 (TRIM6) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 56 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9C030 |
| Gene ID | 117854 |
| Alias | Tripartite motif-containing protein 6,RING finger protein 89,RING-type E3 ubiquitin transferase TRIM6,TRIM6,RNF89 |
| Background | Antibody anti-TRIM6 |
| Status | RUO |
| Note | Mol. Weight 56 kDa |
Descripción
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