TRIM25 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
TRIM25 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08976
tested applications
ELISA, WB, IF, IP
Description
Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma(SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3(PubMed:22452784).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | tripartite motif-containing 25 (TRIM25) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:200-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 71 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q14258 |
| Gene ID | 7706 |
| Alias | E3 ubiquitin/ISG15 ligase TRIM25,Estrogen-responsive finger protein,RING finger protein 147,RING-type E3 ubiquitin transferase,RING-type E3 ubiquitin transferase TRIM25,Tripartite motif-containing protein 25,Ubiquitin/ISG15-conjugating enzyme TRIM25,Zinc finger protein 147,TRIM25,EFP,RNF147,ZNF147 |
| Background | Antibody anti-TRIM25 |
| Status | RUO |
| Note | Mol. Weight 71 kDa |
Descripción
Related Products
Human TRIM25 (E3 ubiquitin/ISG15 ligase TRIM25) ELISA Kit
Ver Producto
TRIM25 antibody
Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma(SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3(PubMed:22452784).
Ver Producto