TPRKB antibody
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935106861
info@markelab.com
name
TPRKB antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08901
tested applications
ELISA, WB
Description
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37(t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP(TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TP53RK binding protein (TPRKB) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 20 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y3C4 |
| Gene ID | 51002 |
| Alias | EKC/KEOPS complex subunit TPRKB,PRPK-binding protein,TP53RK-binding protein,TPRKB |
| Background | Antibody anti-TPRKB |
| Status | RUO |
| Note | Mol. Weight 20 kDa |
Descripción
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Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37(t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP(TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification(By similarity).
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