TOP2A-Specific antibody
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935106861
info@markelab.com
name
TOP2A-Specific antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08868
tested applications
ELISA, WB, IHC, IF, IP
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | topoisomerase(DNA) II alpha 170kDa (TOP2A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:3000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 175 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P11388 |
| Alias | DNA topoisomerase 2-alpha,DNA topoisomerase II, alpha isozyme,TOP2A,TOP2 |
| Background | Antibody anti-TOP2A |
| Status | RUO |
| Note | Mol. Weight 175 kDa |
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Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation(By similarity).
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