TMEM59 antibody
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935106861
info@markelab.com
name
TMEM59 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08787
tested applications
ELISA, IHC, WB, IF
Description
Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3(MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | transmembrane protein 59 (TMEM59) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 41 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BXS4 |
| Gene ID | 9528 |
| Alias | Transmembrane protein 59,Liver membrane-bound protein,TMEM59,C1orf8 |
| Background | Antibody anti-TMEM59 |
| Status | RUO |
| Note | Mol. Weight 41 kDa |
Descripción
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