TLK1 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | tousled-like kinase 1 (TLK1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 85 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UKI8 |
| Gene ID | 9874 |
| Alias | Serine/threonine-protein kinase tousled-like 1,PKU-beta,Tousled-like kinase 1,TLK1,KIAA0137 |
| Background | Antibody anti-TLK1 |
| Status | RUO |
| Note | Mol. Weight 85 kDa |
Descripción
Related Products
TLK1 antibody
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.
Ver Producto
Serine/Threonine-Protein Kinase Tousled-Like 1 (TLK1) Antibody
Rabbit polyclonal antibody against TLK1 protein. Immunogen region is Internal.
Ver Producto
Tousled-Like Kinase 1 (TLK1) Antibody
Tousled-Like Kinase 1 Antibody is a Rabbit Polyclonal antibody against Tousled-Like Kinase 1.
Ver Producto