TLE1 antibody
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935106861
info@markelab.com
name
TLE1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08720
tested applications
ELISA, WB, IHC
Description
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | transducin-like enhancer of split 1(E(sp1) homolog, Drosophila) (TLE1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 8F4 |
| Observed MW | 85 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q04724 |
| Gene ID | 7088 |
| Alias | Transducin-like enhancer protein 1,E(Sp1) homolog,Enhancer of split groucho-like protein 1 (ESG1),TLE1 |
| Background | Antibody anti-TLE1 |
| Status | RUO |
| Note | Mol. Weight 85 kDa |
Descripción
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Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Ver Producto