TFB2M antibody
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935106861
info@markelab.com
name
TFB2M antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08622
tested applications
ELISA, WB
Description
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | transcription factor B2, mitochondrial (TFB2M) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45-50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H5Q4 |
| Gene ID | 64216 |
| Alias | Dimethyladenosine transferase 2, mitochondrial,Hepatitis C virus NS5A-transactivated protein 5 (HCV NS5A-transactivated protein 5),Mitochondrial 12S rRNA dimethylase 2,Mitochondrial transcription factor B2 (h-mtTFB, h-mtTFB2, hTFB2M, mtTFB2),S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2,TFB2M,NS5ATP5 |
| Background | Antibody anti-TFB2M |
| Status | RUO |
| Note | Mol. Weight 45-50 kDa |
Descripción
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TFB2M antibody
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
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