TESPA1 antibody

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935106861
info@markelab.com
name
TESPA1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08602
tested applications
ELISA, WB
Description
Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development(By similarity). Plays a role in T-cell antigen receptor(TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane(MAM) compartment.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | KIAA0748 (TESPA1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 60 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | A2RU30 |
Gene ID | 9840 |
Alias | Protein TESPA1,Thymocyte-expressed positive selection-associated protein 1,TESPA1,KIAA0748 |
Background | Antibody anti-TESPA1 |
Status | RUO |
Note | Mol. Weight 60 kDa |
Descripción
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TESPA1 antibody
Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development(By similarity). Plays a role in T-cell antigen receptor(TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane(MAM) compartment.
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