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Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation(H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs(GAR) in dimethylarginine-containing proteins.
Primary Antibodies
polyclonal
human,mouse,rat
tudor domain containing 3
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IP, IF
73 kDa; 83 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
TDRD3
This product is for research use only.
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a c...
Precio a consultar
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