TCHP antibody
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935106861
info@markelab.com
name
TCHP antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08557
tested applications
ELISA, WB
Description
Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells(PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis(PubMed:25270598).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | trichoplein, keratin filament binding (TCHP) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 61 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BT92 |
| Gene ID | 84260 |
| Alias | Trichoplein keratin filament-binding protein (Protein TCHP),Mitochondrial protein with oncostatic activity (Mitostatin),Tumor suppressor protein,TCHP |
| Background | Antibody anti-TCHP |
| Status | RUO |
| Note | Mol. Weight 61 kDa |
Descripción
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