TCF7L1 antibody
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Description
Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis(By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | transcription factor 7-like 1(T-cell specific, HMG-box) (TCF7L1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 63 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9HCS4 |
| Gene ID | 83439 |
| Alias | Transcription factor 7-like 1,HMG box transcription factor 3 (TCF-3),TCF7L1,TCF3 |
| Background | Antibody anti-TCF7L1 |
| Status | RUO |
| Note | Mol. Weight 63 kDa |
Descripción
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