TBC1D17 antibody
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935106861
info@markelab.com
name
TBC1D17 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08510
tested applications
ELISA, WB, IF, IHC
Description
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TBC1 domain family, member 17 (TBC1D17) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 73 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9HA65 |
| Gene ID | 79735 |
| Alias | TBC1 domain family member 17,TBC1D17 |
| Background | Antibody anti-TBC1D17 |
| Status | RUO |
| Note | Mol. Weight 73-100 kDa |
Descripción
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