TAX1BP1 antibody
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935106861
info@markelab.com
name
TAX1BP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08506
tested applications
ELISA, WB, IHC
Description
TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms with MW 65-68 kDa and 86-91 kDa.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tax1(human T-cell leukemia virus type I) binding protein 1 (TAX1BP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 68 kDa, 85 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q86VP1 |
| Gene ID | 8887 |
| Alias | Tax1-binding protein 1,TRAF6-binding protein,TAX1BP1,T6BP |
| Background | Antibody anti-TAX1BP1 |
| Status | RUO |
| Note | Mol. Weight 68 kDa, 85 kDa |
Descripción
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