TAOK3 antibody
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Description
Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor(EGF).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TAO kinase 3 (TAOK3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 100-105 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H2K8 |
| Gene ID | 51347 |
| Alias | Serine/threonine-protein kinase TAO3,Cutaneous T-cell lymphoma-associated antigen HD-CL-09 (CTCL-associated antigen HD-CL-09),Dendritic cell-derived protein kinase,JNK/SAPK-inhibitory kinase,Jun kinase-inhibitory kinase,Kinase from chicken homolog A (hKFC-A),Thousand and one amino acid protein 3,TAOK3,DPK,JIK,KDS,MAP3K18 |
| Background | Antibody anti-TAOK3 |
| Status | RUO |
| Note | Mol. Weight 100-105 kDa |
Descripción
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