TAF1C antibody
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Description
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa (TAF1C) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 110 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15572 |
| Gene ID | 9013 |
| Alias | TATA box-binding protein-associated factor RNA polymerase I subunit C,RNA polymerase I-specific TBP-associated factor 110 kDa (TAFI110),TATA box-binding protein-associated factor 1C (TBP-associated factor 1C),Transcription initiation factor SL1/TIF-IB subunit C,TAF1C |
| Background | Antibody anti-TAF1C |
| Status | RUO |
| Note | Mol. Weight 110 kDa |
Descripción
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