TAF11 antibody
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Description
Core TAFII present in both of the previously described TFIID species which either lack or contain TAFII30(TFIID alpha and TFIID beta respectively).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TAF11 RNA polymerase II, TATA box binding protein(TBP)-associated factor, 28kDa (TAF11) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 28 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15544 |
| Gene ID | 6882 |
| Alias | Transcription initiation factor TFIID subunit 11,TFIID subunit p30-beta,Transcription initiation factor TFIID 28 kDa subunit (TAF(II)28, TAFII-28, TAFII28),TAF11,TAF2I |
| Background | Antibody anti-TAF11 |
| Status | RUO |
| Note | Mol. Weight 28 kDa |
Descripción
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TAF11 antibody
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.
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