SUN1 antibody

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Description
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration(INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes(NPCs)(By similarity). Required for efficient localization of SYNE4 in the nuclear envelope(By similarity).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | unc-84 homolog A(C. elegans) (SUN1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1:500-1:5000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 90 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | O94901 |
Gene ID | 6821 |
Alias | SUN domain-containing protein 1,Protein unc-84 homolog A,Sad1/unc-84 protein-like 1,SUN1,KIAA0810,UNC84A |
Background | Antibody anti-SUN1 |
Status | RUO |
Note | Mol. Weight 90 kDa |
Descripción
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