SULF2 antibody
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935106861
info@markelab.com
name
SULF2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08375
tested applications
ELISA, WB, IHC
Description
Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | sulfatase 2 (SULF2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 130-150 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8IWU5 |
| Gene ID | 55959 |
| Alias | Extracellular sulfatase Sulf-2 (hSulf-2),Arylsulfatase,N-acetylglucosamine-6-sulfatase,Extracellular sulfatase Sulf-2 secreted form,SULF2,KIAA1247 |
| Background | Antibody anti-SULF2 |
| Status | RUO |
| Note | Mol. Weight 130-150 kDa |
Descripción
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SULF2 antibody
Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
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Sulfatase 2 (SULF2) Antibody
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).
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