STXBP2 antibody
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Description
Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor(SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer(NK) cells.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | syntaxin binding protein 2 (STXBP2) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:1000-1:8000; IHC: 1:50-1:500 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Clone ID | 2C7 |
| Observed MW | 66 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15833 |
| Gene ID | 6813 |
| Alias | Syntaxin-binding protein 2,Protein unc-18 homolog 2 (Unc18-2),Protein unc-18 homolog B (Unc-18B),STXBP2,UNC18B |
| Background | Antibody anti-STXBP2 |
| Status | RUO |
| Note | Mol. Weight 66 kDa |
Descripción
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STXBP2 antibody
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor(SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer(NK) cells.
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