STIM1 antibody

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935106861
info@markelab.com
name
STIM1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08321
tested applications
ELISA, WB, IHC

Description

Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch(By similarity).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
stromal interaction molecule 1 (STIM1)
Host
Mouse
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:200-1:2000
IHC: 1:50-1:500
Clonality
monoclonal
Conjugation
Unconjugated
Isotype
IgG2a
Clone ID
4G6
Observed MW
77kd
Purity
≥95% as determined by SDS-PAGE
Purification
Protein A+G purification
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q13586
Gene ID
6786
Alias
Stromal interaction molecule 1,STIM1,GOK
Background
Antibody anti-STIM1
Status
RUO
Note
Mol. Weight 77 kDa

Descripción

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