STEAP3 antibody
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Description
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | STEAP family member 3 (STEAP3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q658P3 |
| Gene ID | 55240 |
| Alias | Metalloreductase STEAP3,Dudulin-2,Six-transmembrane epithelial antigen of prostate 3,Tumor suppressor-activated pathway protein 6 (hTSAP6),pHyde (hpHyde),STEAP3,TSAP6 |
| Background | Antibody anti-STEAP3 |
| Status | RUO |
| Note | Mol. Weight 55 kDa |
Descripción
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