SSRP1 antibody
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Description
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | structure specific recognition protein 1 (SSRP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Refer to figures |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q08945 |
| Gene ID | 6749 |
| Alias | FACT complex subunit SSRP1,Chromatin-specific transcription elongation factor 80 kDa subunit,Facilitates chromatin transcription complex 80 kDa subunit (FACT 80 kDa subunit, FACTp80),Facilitates chromatin transcription complex subunit SSRP1,Recombination signal sequence recognition protein 1,Structure-specific recognition protein 1 (hSSRP1),T160,SSRP1,FACT80 |
| Background | Antibody anti-SSRP1 |
| Status | RUO |
| Note | Mol. Weight 90 kDa |
Descripción
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