SPTBN1 antibody

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935106861
info@markelab.com
name
SPTBN1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08203
tested applications
ELISA, WB

Description

Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
spectrin, beta, non-erythrocytic 1 (SPTBN1)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
275 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q01082
Gene ID
6711
Alias
Spectrin beta chain, non-erythrocytic 1,Beta-II spectrin,Fodrin beta chain,Spectrin, non-erythroid beta chain 1,SPTBN1,SPTB2
Background
Antibody anti-SPTBN1
Status
RUO
Note
Mol. Weight 275 kDa

Descripción

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SPTBN1 antibody

Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.

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SPTBN1-Specific antibody

SPTBN1 is the non-erythrocytic form of β-spectrin or β-fodrin. Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. Reduced expression of SPTBN1 has been found to correlate with shorter survival of patients with hepatocellular cancer, pancreatic cancer and other malignancies of the gastrointestinal tract, suggesting tumor suppression ability of this protein.

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