SPI1 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Binds to the PU-box, a purine-rich DNA sequence(5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | spleen focus forming virus(SFFV) proviral integration oncogene spi1 (SPI1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 31-38 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P17947 |
| Gene ID | 6688 |
| Alias | Transcription factor PU.1,31 kDa-transforming protein,SPI1 |
| Background | Antibody anti-SPI1 |
| Status | RUO |
| Note | Mol. Weight 31-38 kDa |
Descripción
Related Products
SPI1 antibody
Binds to the PU-box, a purine-rich DNA sequence(5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing(By similarity).
Ver Producto
Recombinant Human SPI1
Ver Producto
Transcription Factor PU.1 (SPI1) Antibody
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Ver Producto