SPATA13 antibody
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935106861
info@markelab.com
name
SPATA13 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08158
tested applications
ELISA, WB, IF
Description
Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | spermatogenesis associated 13 (SPATA13) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 75 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96N96 |
| Gene ID | 221178 |
| Alias | Spermatogenesis-associated protein 13,APC-stimulated guanine nucleotide exchange factor 2 (Asef2),SPATA13 |
| Background | Antibody anti-SPATA13 |
| Status | RUO |
| Note | Mol. Weight 75 kDa |
Descripción
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