SOX7 antibody
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Description
Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors(By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification(By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter(By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SRY(sex determining region Y)-box 7 (SOX7) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 42-45 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BT81 |
| Gene ID | 83595 |
| Alias | Transcription factor SOX-7,SOX7 |
| Background | Antibody anti-SOX7 |
| Status | RUO |
| Note | Mol. Weight 42-45 kDa |
Descripción
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SOX7 antibody
Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors(By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification(By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter(By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.
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