SOS1 antibody

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935106861
info@markelab.com
name
SOS1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08118
tested applications
ELISA, WB, IF

Description

Promotes the exchange of Ras-bound GDP by GTP(PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF(PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor(GEF) activity(By similarity).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
son of sevenless homolog 1 (SOS1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IF: 1:50 - 1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
180 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q07889
Gene ID
6654
Alias
Son of sevenless homolog 1 (SOS-1),SOS1
Background
Antibody anti-SOS1
Status
RUO
Note
Mol. Weight 180 kDa

Descripción

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