SORBS2 antibody
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935106861
info@markelab.com
name
SORBS2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08112
tested applications
ELISA, IP
Description
Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12(PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | sorbin and SH3 domain containing 2 (SORBS2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O94875 |
| Gene ID | 8470 |
| Alias | Sorbin and SH3 domain-containing protein 2,Arg-binding protein 2 (ArgBP2),Arg/Abl-interacting protein 2,Sorbin,SORBS2,ARGBP2,KIAA0777 |
| Background | Antibody anti-SORBS2 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
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