SNUPN antibody
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Description
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine(m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | snurportin 1 (SNUPN) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 41 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95149 |
| Gene ID | 10073 |
| Alias | Snurportin-1,RNA U transporter 1,SNUPN,RNUT1,SPN1 |
| Background | Antibody anti-SNUPN |
| Status | RUO |
| Note | Mol. Weight 41 kDa |
Descripción
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SNUPN antibody
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine(m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2, 2, 7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
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