SNRPB antibody
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935106861
info@markelab.com
name
SNRPB antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08070
tested applications
ELISA, WB, IHC
Description
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | small nuclear ribonucleoprotein polypeptides B and B1 (SNRPB) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 25-30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P14678 |
| Gene ID | 6628 |
| Alias | Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B),Sm protein B/B' (Sm-B/B', SmB/B'),SNRPB,COD,SNRPB1 |
| Background | Antibody anti-SNRPB |
| Status | RUO |
| Note | Mol. Weight 25-30 kDa |
Descripción
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SNRPB antibody
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.
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