SMARCB1 antibody
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935106861
info@markelab.com
name
SMARCB1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10186
tested applications
ELISA, IHC
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 44 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q12824 |
| Gene ID | 6598 |
| Alias | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1,BRG1-associated factor 47 (BAF47),Integrase interactor 1 protein,SNF5 homolog (hSNF5),SMARCB1,BAF47,INI1,SNF5L1 |
| Background | Antibody anti-SMARCB1 |
| Status | RUO |
| Note | Mol. Weight 44 kDa |
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SMARCB1 antibody
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.
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