MIEF1 antibody
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Description
Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa(also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Smith-Magenis syndrome chromosome region, candidate 7-like (MIEF1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 49 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NQG6 |
| Alias | Mitochondrial dynamics protein MIEF1,Mitochondrial dynamics protein of 51 kDa,Mitochondrial elongation factor 1,Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like (SMCR7-like protein),MIEF1,MID51,SMCR7L |
| Background | Antibody anti-MIEF1 |
| Status | RUO |
| Note | Mol. Weight 49 kDa |
Descripción
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