SMC3 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | structural maintenance of chromosomes 3 (SMC3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 140 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UQE7 |
| Gene ID | 9126 |
| Alias | Structural maintenance of chromosomes protein 3 (SMC protein 3, SMC-3),Basement membrane-associated chondroitin proteoglycan (Bamacan),Chondroitin sulfate proteoglycan 6,Chromosome-associated polypeptide (hCAP),SMC3,BAM,BMH,CSPG6,SMC3L1 |
| Background | Antibody anti-SMC3 |
| Status | RUO |
| Note | Mol. Weight 140 kDa |
Descripción
Related Products
SMC3 antibody
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Ver Producto
Structural Maintenance of Chromosomes Protein 3 (SMC3) Antibody
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.
Ver Producto
Human Structural Maintenance Of Chromosomes Protein 3 (SMC3) Protein
Human Structural Maintenance Of Chromosomes Protein 3 (SMC3) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto