Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Primary Antibodies
polyclonal
human,mouse,rat
structural maintenance of chromosomes 3
Rabbit
IgG
Unconjugated
liquid
ELISA, WB
140 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
SMC3
BAM, BMH, CSPG6, SMC3L1
This product is for research use only.
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may ...
Precio a consultar
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