SMARCAL1 antibody
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Description
ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A(RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 (SMARCAL1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 106 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NZC9 |
| Gene ID | 50485 |
| Alias | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1,HepA-related protein (hHARP),Sucrose nonfermenting protein 2-like 1,SMARCAL1,HARP |
| Background | Antibody anti-SMARCAL1 |
| Status | RUO |
| Note | Mol. Weight 106 kDa |
Descripción
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