Mediates electroneutral sodium-and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity(By similarity).
Primary Antibodies
polyclonal
human,mouse,rat
solute carrier family 4, sodium bicarbonate cotransporter, member 8
Rabbit
IgG
Unconjugated
liquid
ELISA, WB
121 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
SLC4A8
Ndcbe1
This product is for research use only.
Mediates electroneutral sodium-and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2...
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