Slc4a8 antibody

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935106861
info@markelab.com
name
Slc4a8 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07968
tested applications
ELISA, WB
Description
Mediates electroneutral sodium-and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity(By similarity).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | solute carrier family 4, sodium bicarbonate cotransporter, member 8 (Slc4a8) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 121 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q6RVG2 |
Gene ID | 315311 |
Alias | Electroneutral sodium bicarbonate exchanger 1,Electroneutral Na+-driven Cl-HCO3 exchanger,Solute carrier family 4 member 8,k-NBC3,Slc4a8,Ndcbe1 |
Background | Antibody anti-Slc4a8 |
Status | RUO |
Note | Mol. Weight 121 kDa |
Descripción
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Slc4a8 antibody
Mediates electroneutral sodium-and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity(By similarity).
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