SLC22A2 antibody
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Description
Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline(norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide(NMN), tetraethylammonium(TEA), 1-methyl-4-phenylpyridinium(MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | solute carrier family 22(organic cation transporter), member 2 (SLC22A2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60-70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O15244 |
| Gene ID | 6582 |
| Alias | Solute carrier family 22 member 2,Organic cation transporter 2 (hOCT2),SLC22A2,45567 |
| Background | Antibody anti-SLC22A2 |
| Status | RUO |
| Note | Mol. Weight 60-70 kDa |
Descripción
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