SH3BP1 antibody
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Description
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SH3-domain binding protein 1 (SH3BP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 76-80 kDa,51 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y3L3 |
| Gene ID | 23616 |
| Alias | SH3 domain-binding protein 1,SH3BP1 |
| Background | Antibody anti-SH3BP1 |
| Status | RUO |
| Note | Mol. Weight 76-80 kDa, 51 kDa |
Descripción
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