SETDB2 antibody
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935106861
info@markelab.com
name
SETDB2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07772
tested applications
ELISA, WB
Description
Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3(H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1(CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SET domain, bifurcated 2 (SETDB2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 101 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96T68 |
| Gene ID | 83852 |
| Alias | Histone-lysine N-methyltransferase SETDB2,Chronic lymphocytic leukemia deletion region gene 8 protein,Lysine N-methyltransferase 1F,SET domain bifurcated 2,SETDB2,C13orf4,CLLD8,KMT1F |
| Background | Antibody anti-SETDB2 |
| Status | RUO |
| Note | Mol. Weight 101 kDa |
Descripción
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