SETDB1 antibody

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935106861
info@markelab.com
name
SETDB1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07771
tested applications
ELISA, WB, IHC
Description
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SET domain, bifurcated 1 (SETDB1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 210 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15047 |
| Gene ID | 9869 |
| Alias | Histone-lysine N-methyltransferase SETDB1,ERG-associated protein with SET domain (ESET),Histone H3-K9 methyltransferase 4 (H3-K9-HMTase 4),Lysine N-methyltransferase 1E,SET domain bifurcated 1,SETDB1,ESET,KIAA0067,KMT1E |
| Background | Antibody anti-SETDB1 |
| Status | RUO |
| Note | Mol. Weight 210 kDa |
Descripción
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Human SETDB1 (Histone-lysine N-methyltransferase SETDB1) ELISA Kit
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SETDB1 antibody
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
Ver Producto