SETD1B antibody

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935106861
info@markelab.com
name
SETD1B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07766
tested applications
ELISA, WB, IP, IHC,IF

Description

Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase(HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
SET domain containing 1B (SETD1B)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
260 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IP, IHC,IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9UPS6
Gene ID
23067
Alias
Histone-lysine N-methyltransferase SETD1B,Lysine N-methyltransferase 2G,SET domain-containing protein 1B (hSET1B),SETD1B,KIAA1076,KMT2G,SET1B
Background
Antibody anti-SETD1B
Status
RUO
Note
Mol. Weight 260 kDa

Descripción

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