SETD1B antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase(HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | SET domain containing 1B (SETD1B) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 260 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IP, IHC,IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q9UPS6 |
Gene ID | 23067 |
Alias | Histone-lysine N-methyltransferase SETD1B,Lysine N-methyltransferase 2G,SET domain-containing protein 1B (hSET1B),SETD1B,KIAA1076,KMT2G,SET1B |
Background | Antibody anti-SETD1B |
Status | RUO |
Note | Mol. Weight 260 kDa |
Descripción
Related Products

SETD1B antibody
Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase(HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.
Ver Producto
Recombinant Human SETD1B
Ver Producto
Histone-Lysine N-Methyltransferase SETD1B (SETD1B) Antibody
Histone-Lysine N-Methyltransferase SETD1B Antibody is a Rabbit Polyclonal antibody against Histone-Lysine N-Methyltransferase SETD1B.
Ver Producto