SERPINE2 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | serpin peptidase inhibitor, clade E(nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 44-50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P07093 |
| Gene ID | 5270 |
| Alias | GDN,PI7,PN1,PNI,PI-7,PN-1,GDNPF,Glia-derived nexin,Peptidase inhibitor 7,Protease nexin 1,Protease nexin I,Serpin E2 |
| Background | Antibody anti-SERPINE2 |
| Status | RUO |
| Note | Mol. Weight 44-50 kDa |
Descripción
SERPINE2, also known as protease nexin-1 (PN-1), is a member of the serpin (serine protease inhibitor) superfamily, which is involved in regulating a wide variety of proteases across different physiological processes. Unlike its closely related counterpart, SERPINE1 (PAI-1), which predominantly regulates fibrinolysis, SERPINE2 plays a more diverse role in modulating tissue remodeling, inflammation, and cellular homeostasis by inhibiting a variety of proteases. These include thrombin, trypsin, urokinase-type plasminogen activator (uPA), and other serine proteases that participate in hemostasis, extracellular matrix degradation, and inflammation. SERPINE2 is expressed in a wide range of tissues, including the brain, lungs, kidneys, and cardiovascular system. Its ability to inhibit multiple serine proteases grants it a broad functional role in physiological processes ranging from coagulation to inflammation.
Related Products
SERPINE2 antibody
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Ver Producto
Glia Derived Nexin / GDN (SERPINE2) Antibody
SERPINE2 Antibody is a Rabbit Polyclonal antibody against SERPINE2. This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
Ver Producto
Human Glia Derived Nexin / GDN (SERPINE2) ELISA Kit
Human Glia Derived Nexin / GDN (SERPINE2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Glia Derived Nexin concentrations in Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Ver Producto