SEPTIN5 antibody
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Description
Filament-forming cytoskeletal GTPase(By similarity). May play a role in cytokinesis(Potential). May play a role in platelet secretion(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | septin 5 (SEPTIN5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 43 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q99719 |
| Gene ID | 5413 |
| Alias | Septin-5,Cell division control-related protein 1 (CDCrel-1),Peanut-like protein 1,SEPTIN5,PNUTL1,SEPT5 |
| Background | Antibody anti-SEPTIN5 |
| Status | RUO |
| Note | Mol. Weight 43 kDa |
Descripción
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Septin 5 (SEPTIN5) Antibody
This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq].
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